Endocrine Abstracts

Introduction: Pneumomediastinum is a rare complication of diabetic ketoacidosis (DKA). The pathophysiology of DKA commonly associated with changes in pressure gradients in the pulmonary alveoli secondary to vomiting and/or Kussmaul respiration. We report a 21-year-old male with DKA who have no history of diabetes mellitus before and was found to have pneumomediastinum and subcutaneous emphysema.Case: A 21-year-old male without previous history of diabete...

Thyroxine-binding globulin (TBG), the major transport protein for thyroid hormone in circulation, is synthesized in the liver. Complete TBG deficiency was first reported in 1964, and in 1991 a single nucleotide deletion was found in the first base of the codon for amino acid 352 of the common-type TBG molecule. This mutation causes a frameshift in translation and premature termination. Most people with abnormal TBG concentrations are euthyroid. Cases of Graves’ disease wi...

Current guidelines on cardiovascular (CV) disease prevention recommend targeted management after assessment of CV risks using many of available method even if the patient is asymptomatic. This study was performed to explore how CV high-risk is differently detected between two distinct methods: non-invasive test (NIT) and risk calculation and how the awareness of CV high-risk impacts physician and patient behavior for risk management in diabetes patient.A...